Melanoma And Skin Cancer Trials Limited

This study tests whether the immunotherapy drug avelumab can help prevent Merkel cell carcinoma from coming back after initial treatment. About 122 people with stage I to III Merkel cell carcinoma are randomly assigned to receive either avelumab or a placebo. The main goal is to …

This study tests whether adding a type of radiation therapy (PRRT or standard radiotherapy) to the immunotherapy drug avelumab can help control metastatic Merkel cell carcinoma, a rare and aggressive skin cancer. About 19 adults with advanced disease that hasn't been treated befo…

This phase 3 trial tests whether a cream containing sirolimus, applied nightly for 24 weeks, can prevent facial skin cancers in people who have received an organ transplant. The study includes 146 adults who have had a transplant at least a year ago and have a history of skin can…