Mario Negri Institute For Pharmacological Research
Clinical trials sponsored by Mario Negri Institute For Pharmacological Research, explained in plain language.
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New study aims to spare women from chemo and major surgery for common breast cancer
Disease control Not yet recruitingThis study tests whether a genetic test (Oncotype DX) can help decide if women with a common type of early breast cancer (HR+/HER2-) can skip chemotherapy and instead receive a targeted drug (abemaciclib) plus hormone therapy before surgery. The goal is to see if this approach al…
Phase: PHASE2 • Sponsor: Mario Negri Institute for Pharmacological Research • Aim: Disease control
Last updated Apr 29, 2026 15:14 UTC
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Scientists hunt for clues to personalize kidney disease treatment
Knowledge-focused Not yet recruitingThis study looks at stored blood and kidney samples from 120 people with membranous nephropathy (a kidney disease) to find biological markers that can predict who will respond to the drug rituximab. Researchers will analyze genetic, protein, and metabolic data to create a persona…
Sponsor: Mario Negri Institute for Pharmacological Research • Aim: Knowledge-focused
Last updated May 01, 2026 15:58 UTC
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Wearable listens for trouble in dialysis patients
Knowledge-focused Not yet recruitingThis study tests a new wearable device that records sounds from the blood vessel connection used for dialysis. Six adults on hemodialysis will wear the device weekly for 8 weeks to see if it can detect changes as well as a standard stethoscope. The goal is to find a simpler way t…
Phase: NA • Sponsor: Mario Negri Institute for Pharmacological Research • Aim: Knowledge-focused
Last updated Apr 26, 2026 20:01 UTC