Liverpool School Of Tropical Medicine

This trial tests whether two antiviral drugs, favipiravir and ribavirin, can help clear the virus faster in adults hospitalized with Crimean-Congo hemorrhagic fever (CCHF), a severe tick-borne infection. Participants will receive one of the drugs or optimized standard care, and r…

This study tests different ways to deliver malaria prevention medicine to children under 10 who were hospitalized with severe malaria or severe anemia in Kenya. The goal is to see which method helps more children take all their doses and avoid getting sick again. About 600 childr…

This study tests newer antimalarial drugs to see if they work as well as the current standard treatment for malaria in early pregnancy. It involves 1,510 pregnant women in Africa. The goal is to find treatments that are both effective and safe for the mother and baby.

This study will test whether a new urine-based test can accurately diagnose pneumococcal pneumonia in children under 5 in Malawi. Researchers will use 350 stored urine samples from healthy kids and those with pneumonia, comparing results to standard lab methods. If it works, this…

This study is testing a new rapid diagnostic test for Crimean-Congo hemorrhagic fever (CCHF) that gives results in 20 minutes. Researchers will enroll 492 adults in Turkey with suspected CCHF to see if the test is accurate compared to standard lab methods. The goal is to provide …

This study looks at whether CPAP, a machine that pushes air through a mask at night, can help people with large airway collapse (LAC). LAC causes shortness of breath, cough, and wheeze, and is often mistaken for asthma. The study will test if a larger trial is possible by checkin…

This study will survey 32,000 households in Ghana and Rwanda to understand where snakebites happen most. Researchers will use GPS and computer models to create risk maps. The goal is to help health officials send antivenom to the areas that need it most and plan prevention effort…

This study will check the lung health of 50 adults who finished treatment for tuberculosis (TB) in Liverpool, UK, about one year after their treatment ended. Participants will take a breathing test and answer questions about their health and wellbeing. The goal is to find out how…