Jiangsu Hengrui Medicine Co., Ltd.

This study tests a new drug, HRS-4357, against current standard treatments for men with a specific type of advanced prostate cancer (PSMA-positive, castration-resistant) that has spread. About 370 men will be randomly assigned to receive either HRS-4357 or a standard therapy. The…

This phase 3 trial tests a new drug called SHR-A1811 against standard chemotherapy in 300 people with ovarian, fallopian tube, or primary peritoneal cancer that no longer responds to platinum-based treatment. The goal is to see if the new drug can slow cancer growth and improve s…

This study tests a new drug called SHR-A1904 in people with advanced solid tumors, specifically stomach or pancreatic cancer that has not responded to other treatments. The goal is to find the safest dose and see if the drug can shrink tumors. About 83 adults will take part in th…

This study tests a new drug (HRS-1167) combined with two standard treatments (abiraterone and prednisone) in 66 men with metastatic prostate cancer. The goal is to find the safest dose and see if the combo works better at controlling the disease. Participants must have advanced c…

This study tests a new drug called SHR-A1811 against a standard chemotherapy combination for people with early-stage or locally advanced HER2-positive breast cancer. About 740 women will receive either the new drug or standard treatment before surgery. The goal is to see if the n…

This study is testing a new drug called SHR-4394 combined with other anti-cancer treatments for men with prostate cancer. The goal is to find the safest dose and see if the combination can lower PSA levels, a key marker of prostate cancer. About 100 men aged 18 to 85 will take pa…

This study tests an experimental drug, hetrombopag, to see if it can safely raise platelet counts in cancer patients whose platelets drop too low after chemotherapy. About 150 adults with solid tumors (like lung, breast, or colon cancer) will receive either the drug or a placebo …

This study tests a new drug, SHR-A1811, against standard treatments for people with advanced or metastatic non-small cell lung cancer that has a specific change in the HER2 gene. About 300 participants who have not had prior treatment for advanced disease will be enrolled. The go…

This study tests two experimental drugs (HS-20093 or SHR2554) given together with standard hormone therapy in men with metastatic prostate cancer. The goal is to see if the combinations are safe and help lower PSA levels, a marker of cancer activity. About 218 men aged 18 to 80 w…

This study tests whether adding a new drug (SHR4640) to a standard gout medication (febuxostat) works better than just increasing the dose of febuxostat alone. About 340 adults with gout and high uric acid who are not well-controlled on 40 mg of febuxostat will take either the co…

This early-stage study tests an experimental drug called HRS-6093 in people with advanced solid tumors that have a specific KRAS G12D mutation. The main goals are to check safety, find the right dose, and see early signs of tumor shrinkage. About 153 adults aged 18-75 who have ex…

This study tests a new drug called HRS-5041, taken as a pill, combined with other cancer treatments for men with advanced prostate cancer. The goal is to see if the combination is safe and helps control the cancer. About 100 men aged 18 to 80 will take part. The study is currentl…

This early-stage study tests a new drug, HRS-3005, in 190 adults with B-cell blood cancers that have returned or not responded to prior treatment. The main goals are to check the drug's safety, find the best dose, and see if it can shrink tumors. Participants must be in fairly go…

This study tests two different drug combinations for people with advanced HER2-positive non-small cell lung cancer. The goal is to see if these combos can shrink tumors and control the disease. About 324 adults aged 18-75 with good performance status are being enrolled. This is a…

This study tests a new drug, HRS-9190, against a standard muscle relaxant used during surgery. About 60 adults having planned surgery will get one of the two drugs. The main goal is to see how fast muscles recover after the drug is stopped. Researchers will also check for side ef…

This early-stage study tests a new drug called HRS-7172 in people with advanced solid tumors that have RAS mutations or amplifications. The main goals are to check safety, find the best dose, and see how the body processes the drug. About 120 adults aged 18-75 with good organ fun…

This phase 3 study tests whether a new drug, rezvilutamide, works better than the standard drug enzalutamide for men with low-volume metastatic hormone-sensitive prostate cancer. Both drugs are combined with hormone therapy (ADT). The study aims to see which treatment lowers PSA …

This phase 3 trial tests a new combination of drugs (irinotecan liposome, oxaliplatin, 5-FU, and calcium folinate) against a standard combination (nab-paclitaxel and gemcitabine) as the first treatment for people with metastatic pancreatic cancer. The study will enroll about 662 …

This study tests a long-acting painkiller (bupivacaine liposome) injected near the spine to control pain after lung surgery. About 96 adults having a specific type of lung surgery will receive either the new drug or a standard painkiller. The goal is to see if the new drug provid…

This study looks at a painkiller called bupivacaine liposome injection, given during surgery to help control pain afterward. It involves 232 children aged 6 to 17 having orthopedic (bone) surgery. The goal is to see if it safely reduces pain and the need for stronger opioid pain …

This early-stage study tests different doses of an experimental diabetes drug called SHR-3167 in 60 healthy adults aged 18 to 55. The goal is to measure how much of the drug gets into the blood and how safe it is, not to treat any disease. Participants will receive a single injec…

This early-stage study tests the safety and tolerability of a new injectable drug called HRS-2183 in 42 healthy Chinese adults aged 18-45. Participants receive either a single dose or multiple doses to see how the drug moves through the body and if it causes any side effects. Thi…