Jena University Hospital

This study is testing whether treating a common herpes virus improves survival in critically ill pneumonia patients on breathing machines. Researchers will randomly assign over 600 patients to receive either the antiviral drug acyclovir or no antiviral treatment for 10 days. The …

This study aims to find the best way to prevent strokes in people with a common heart rhythm problem (atrial fibrillation) who have already suffered a dangerous brain bleed. Researchers are comparing a one-time heart implant that closes off a small pouch in the heart to long-term…

This study is testing if a drug called bortezomib, already used for a type of blood cancer, can help people with severe autoimmune encephalitis. In this condition, the body's immune system mistakenly attacks the brain. The trial will see if bortezomib safely reduces these harmful…

This study aims to understand how well common blood tests reflect actual heart muscle damage after valve surgery. Researchers will enroll 100 patients undergoing aortic or mitral valve surgery and compare their blood test results with detailed heart MRI scans. The goal is to impr…

This study aims to understand if analyzing bile acid patterns in pregnant women with intrahepatic cholestasis of pregnancy (ICP) can help predict risks to the baby. Researchers will compare blood and stool samples from women with ICP, healthy pregnant women, and healthy non-pregn…