Incyte Corporation

This study tested whether adding the targeted drug ruxolitinib to standard chemotherapy could help children with a high-risk form of acute lymphoblastic leukemia (ALL). The trial included 171 children and young adults aged 1 to 21. The goal was to see if the combination was safe …

This study tested a drug called itacitinib in people with myelofibrosis (a serious bone marrow disease) who had already been treated with ruxolitinib or fedratinib. The goal was to see if itacitinib is safe and can shrink an enlarged spleen, a common problem in this condition. On…

This study tested an experimental drug called povorcitinib in 136 adults with chronic spontaneous urticaria (hives) that standard treatments couldn't control. The goal was to see if the drug could reduce itching and hives over 12 weeks. Participants continued their usual antihist…

This study tested whether adding the immunotherapy drug INCMGA00012 to standard chemotherapy (carboplatin-paclitaxel) helps people with advanced anal cancer that cannot be removed by surgery. The trial included 308 adults who had not received chemotherapy for this condition. Rese…

This study tested a drug called pemigatinib in 47 people with rare blood cancers that have a specific genetic change (FGFR1 rearrangement). The goal was to see if the drug could shrink or eliminate the cancer. The treatment helped some patients achieve a complete response, meanin…

This study tested a cream called ruxolitinib on 49 people with genital vitiligo, a condition that causes white patches on the genitals. Participants applied the cream twice a day for up to 48 weeks to see if it made the patches less noticeable. The goal was to find out if the cre…

This study tested whether adding epacadostat to pembrolizumab (an immunotherapy) works better than pembrolizumab alone or standard chemotherapy for people with advanced head and neck cancer that has come back or spread. The trial enrolled 89 adults whose cancer could be measured …

This study tested a cream called ruxolitinib on adults with moderate eczema who didn't get better with standard treatments. The goal was to see if the cream could reduce skin redness, itching, and rash. 241 adults took part, and the study compared the cream to a placebo (a cream …

This study tested a new microneedle patch to collect fluid from the skin of 20 healthy volunteers and people with eczema (atopic dermatitis). The goal was to see how much fluid could be collected and how well it was tolerated. This early-stage research aims to improve how we samp…

This study looked at how three common drugs (an antifungal, an antibiotic, and acid reducers) change the levels of a new medicine called INCB161734 in the blood. 63 healthy adults aged 18-55 took part. The goal was to gather safety and drug interaction information, not to treat a…

This study looked at how a single dose of the drug INCB099280 is absorbed, broken down, and removed from the body. Five healthy men took one pill, and researchers measured the drug and its byproducts in their blood, urine, and stool. The goal was to understand the drug's journey,…