New pill tested to tame uncontrollable hives

NCT ID NCT05936567

Completed Disease control Sponsor: Incyte Corporation Source: ClinicalTrials.gov ↗

Summary

This study tested an oral medication called povorcitinib for adults with chronic spontaneous urticaria (long-lasting, unpredictable hives) that standard antihistamines could not control. The goal was to see if different doses of the drug could safely reduce hive and itch severity over 12 weeks compared to a placebo. The trial was completed with 136 participants.

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Contacts and locations

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Locations

Allergy and Asthma Center of Charleston

Charleston, South Carolina, 29407, United States
Allergy and Asthma Consultants, Pc

Redwood City, California, 94063, United States
Antelope Valley Clinical Trials Lancaster Office

Palmdale, California, 93551, United States
Arkansas Research Trials

North Little Rock, Arkansas, 72117, United States
Bellingham Asthma, Allergy Immunology Clinic

Bellingham, Washington, 98225, United States
Cahaba Dermatology

Birmingham, Alabama, 35244, United States
Central Sooner Research

Oklahoma City, Oklahoma, 73170, United States
Centrum Alergologii Sp Z.O.O

Lublin, 20-552, Poland
Centrum Medyczne Pratia Katowice I

Katowice, 40-081, Poland
Charite Universitaetsmedizin Berlin - Campus Benjamin Franklin

Berlin, 12200, Germany
Clinical Research Center of Alabama

Birmingham, Alabama, 35209, United States
DC-MED

Swidnica, 58-100, Poland
David Fivenson, Md, Dermatology, Pllc

Ann Arbor, Michigan, 48103, United States
Delricht Research

New Orleans, Louisiana, 70115, United States
Dermdox Center For Dermatology

Sugarloaf, Pennsylvania, 18249, United States
Etg Warszawa

Warsaw, 02-793, Poland
First Oc Dermatology

Fountain Valley, California, 92708, United States
Foothills Research Center

Scottsdale, Arizona, 85260, United States
Klifos - Klinische Forschung Osnabruck

Osnabrück, 49074, Germany
Klinika Ambroziak

Warsaw, 02-953, Poland
Little Rock Allergy Asthma, Pa Clinical Research Center Lraac

Little Rock, Arkansas, 72205, United States
Melita Medical Sp. Z O. O.

Wroclaw, 50-449, Poland
Mensingderma Research Gmbh

Hamburg, 22391, Germany
Midwest Allergy Sinus Asthma, Sc

Normal, Illinois, 61761, United States
Newport Native Md

Newport Beach, California, 92663, United States
Optimed Research Ltd

Columbus, Ohio, 43235, United States
Panstwowy Instytut Medyczny Ministerstwa Spraw Wewnetrznych Administracji

Warsaw, 02-507, Poland
Rainey and Finklea Dermatology

San Antonio, Texas, 78212, United States
Revival Research Institute, Llc Troy

Troy, Michigan, 48084, United States
Solumed Centrum Medyczne

Poznan, 60-529, Poland
Specderm Poznanska

Bialystok, 15-375, Poland
Specjalistyczny Nzoz Alergologia Plus

Poznan, 60-693, Poland
The Clinical Research Center Crc, Llc

St Louis, Missouri, 63141, United States
Treasure Valley Medical Research

Boise, Idaho, 83706, United States
Universitaetsklinikum Carl Gustav Carus Tu Dresden

Dresden, 01307, Germany
Universitaetsklinikum Schleswig-Holstein - Campus Kiel

Kiel, 24105, Germany
Universitats-Hautklink Tubingen

Tübingen, 72076, Germany
Universitatsklinikum Frankfurt

Frankfurt, 60590, Germany
Universitatsklinikum Leipzig Aor

Leipzig, 04103, Germany
Universitatsmedizin Der Johannes Gutenberg-Universitat Mainz Iii

Mainz, 55131, Germany
University Clinical Hospital

Opole, 45-401, Poland
Vital Prospects Clinical Research Institute, Pc Vpcri

Tulsa, Oklahoma, 74136, United States

Conditions

Explore the condition pages connected to this study.

ANGIOEDEMA CHRONIC IDIOPATHIC URTICARIA CHRONIC SPONTANEOUS URTICARIA HIVES PRURITIS URTICARIA