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New drug shows promise for controlling chronic hives

NCT ID NCT05936567

Completed Disease control Sponsor: Incyte Corporation Source: ClinicalTrials.gov ↗

Summary

This study tested whether a new oral medication called povorcitinib could help adults with chronic spontaneous urticaria (CSU), a condition causing persistent hives and itching that doesn't respond well to standard antihistamines. Researchers compared different doses of the drug against a placebo in 136 participants over 12 weeks to see if it reduced hive and itch severity. The main goal was to see if the drug was effective and safe for controlling this difficult-to-manage skin condition.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Allergy and Asthma Center of Charleston

    Charleston, South Carolina, 29407, United States

  • Allergy and Asthma Consultants, Pc

    Redwood City, California, 94063, United States

  • Antelope Valley Clinical Trials Lancaster Office

    Palmdale, California, 93551, United States

  • Arkansas Research Trials

    North Little Rock, Arkansas, 72117, United States

  • Bellingham Asthma, Allergy Immunology Clinic

    Bellingham, Washington, 98225, United States

  • Cahaba Dermatology

    Birmingham, Alabama, 35244, United States

  • Central Sooner Research

    Oklahoma City, Oklahoma, 73170, United States

  • Centrum Alergologii Sp Z.O.O

    Lublin, 20-552, Poland

  • Centrum Medyczne Pratia Katowice I

    Katowice, 40-081, Poland

  • Charite Universitaetsmedizin Berlin - Campus Benjamin Franklin

    Berlin, 12200, Germany

  • Clinical Research Center of Alabama

    Birmingham, Alabama, 35209, United States

  • DC-MED

    Swidnica, 58-100, Poland

  • David Fivenson, Md, Dermatology, Pllc

    Ann Arbor, Michigan, 48103, United States

  • Delricht Research

    New Orleans, Louisiana, 70115, United States

  • Dermdox Center For Dermatology

    Sugarloaf, Pennsylvania, 18249, United States

  • Etg Warszawa

    Warsaw, 02-793, Poland

  • First Oc Dermatology

    Fountain Valley, California, 92708, United States

  • Foothills Research Center

    Scottsdale, Arizona, 85260, United States

  • Klifos - Klinische Forschung Osnabruck

    Osnabrück, 49074, Germany

  • Klinika Ambroziak

    Warsaw, 02-953, Poland

  • Little Rock Allergy Asthma, Pa Clinical Research Center Lraac

    Little Rock, Arkansas, 72205, United States

  • Melita Medical Sp. Z O. O.

    Wroclaw, 50-449, Poland

  • Mensingderma Research Gmbh

    Hamburg, 22391, Germany

  • Midwest Allergy Sinus Asthma, Sc

    Normal, Illinois, 61761, United States

  • Newport Native Md

    Newport Beach, California, 92663, United States

  • Optimed Research Ltd

    Columbus, Ohio, 43235, United States

  • Panstwowy Instytut Medyczny Ministerstwa Spraw Wewnetrznych Administracji

    Warsaw, 02-507, Poland

  • Rainey and Finklea Dermatology

    San Antonio, Texas, 78212, United States

  • Revival Research Institute, Llc Troy

    Troy, Michigan, 48084, United States

  • Solumed Centrum Medyczne

    Poznan, 60-529, Poland

  • Specderm Poznanska

    Bialystok, 15-375, Poland

  • Specjalistyczny Nzoz Alergologia Plus

    Poznan, 60-693, Poland

  • The Clinical Research Center Crc, Llc

    St Louis, Missouri, 63141, United States

  • Treasure Valley Medical Research

    Boise, Idaho, 83706, United States

  • Universitaetsklinikum Carl Gustav Carus Tu Dresden

    Dresden, 01307, Germany

  • Universitaetsklinikum Schleswig-Holstein - Campus Kiel

    Kiel, 24105, Germany

  • Universitats-Hautklink Tubingen

    Tübingen, 72076, Germany

  • Universitatsklinikum Frankfurt

    Frankfurt, 60590, Germany

  • Universitatsklinikum Leipzig Aor

    Leipzig, 04103, Germany

  • Universitatsmedizin Der Johannes Gutenberg-Universitat Mainz Iii

    Mainz, 55131, Germany

  • University Clinical Hospital

    Opole, 45-401, Poland

  • Vital Prospects Clinical Research Institute, Pc Vpcri

    Tulsa, Oklahoma, 74136, United States

Conditions

Explore the condition pages connected to this study.

ANGIOEDEMA CHRONIC IDIOPATHIC URTICARIA CHRONIC SPONTANEOUS URTICARIA HIVES PRURITIS URTICARIA