Huyabio International, Llc.

This study tests whether adding HBI-8000 to the standard immunotherapy nivolumab helps people with advanced melanoma that has spread or cannot be removed by surgery. About 450 adults with melanoma not previously treated with PD-1 or PD-L1 inhibitors will receive either the combin…

This early-stage study tests an experimental pill called HBI-2376 in people with advanced solid tumors (like lung, colon, or pancreatic cancer) that have specific gene changes (KRAS or EGFR mutations). The main goals are to find the safest dose and understand how the drug moves t…

This early-stage study tests a new drug, HBI-2438, in people with advanced cancers (like lung, colon, or pancreatic) that have a specific genetic mutation called KRAS G12C. The main goals are to find a safe dose and understand how the drug moves through the body. About 44 adults …

This study tests a single 30-minute IV infusion of HBI 3000 in 150 adults aged 18 to 80 who have had atrial fibrillation for 2 to 72 hours. The goal is to see if the drug can safely and quickly convert the heart back to a normal rhythm. The trial first finds the best dose in an o…