Hugo W. Moser Research Institute At Kennedy Krieger, Inc.

This study looks at why children with Cornelia de Lange syndrome (CdLS) develop problem behaviors like aggression or self-injury, and tests a behavioral treatment to reduce them. Twenty children with CdLS and their families will take part. The treatment involves two full days and…

This study looks at whether JORNAY PM, a stimulant taken at night, can safely improve ADHD symptoms in children who also have epilepsy. About 25 kids will take the medication and be monitored for changes in attention and behavior. The goal is to ease ADHD symptoms without worseni…

This study tests whether a special training method can help people with cerebellar ataxia improve their reaching movements. Researchers will compare this new approach to standard practice in 18 adults aged 22-80 who have ataxia from stroke, tumor, or degeneration. The goal is to …

This study tests whether a gentle electrical stimulation applied to the skin over the spine (called transcutaneous spinal cord stimulation) is safe and can improve walking in children aged 3–16 with incomplete spinal cord injury. Twenty children will receive either real stimulati…

This study tests a new telehealth program called DINOSAUR designed to reduce anxiety in young children (ages 4-6) with autism. The program uses cognitive-behavioral therapy adapted for autistic kids and focuses on helping them cope with uncertainty. Researchers will enroll 70 chi…

This study compares telehealth parent coaching to in-person coaching for improving social-communication skills in toddlers with autism or social communication delays. About 188 children aged 18-33 months and their parents will participate. The goal is to see if online coaching wo…

This study aims to understand why people with Long COVID (PASC) feel so fatigued. Researchers will use brain scans and effort-based tasks to compare 200 adults with PASC to healthy controls. The goal is to find brain changes that could lead to new treatments or rehabilitation str…

This study tests whether different types of appointment reminders and extra support from a patient navigator can help families attend their scheduled visits for autism and neurodevelopmental assessments. About 5,000 patients will be enrolled, and researchers will track which remi…

This study looks at how sleep, physical activity, and daily body rhythms are linked to ADHD symptoms in 200 children. Kids wear a wristband for two weeks to track movement and sleep, and complete brain scans and thinking tasks. The goal is to better understand why ADHD affects pe…

This study tests a new way to train parents of infants with brachial plexus birth injury (a nerve injury that can cause arm weakness). The goal is to see if the training helps parents feel more confident and do daily stretching exercises more consistently, which may prevent shoul…

This study aims to understand how the brain decides how much effort to put into tasks, both mental and physical. Researchers will observe 185 healthy adults using brain scans and behavioral tests to see how fatigue and rewards change our perception of effort. The goal is to learn…