Henan Cancer Hospital

This study examines the effectiveness and safety of anlotinib, a targeted therapy, for people with advanced non-small cell or small cell lung cancer who have already tried anlotinib and it stopped working. Researchers will review medical records from multiple hospitals to see if …

This study looks at how well three different antibody-based drug combinations work as the first treatment for people with a rare type of blood cancer called marginal zone lymphoma (MZL). About 131 adults who have not yet been treated will receive one of three regimens based on th…

This study tests whether adding the drug adebrelimab after standard chemotherapy and radiation can help keep limited-stage small cell lung cancer from growing back. About 200 adults with untreated cancer will receive either standard treatment alone or standard treatment followed …

This study tests whether adding the immunotherapy drug toripalimab to chemotherapy before surgery can improve outcomes for people with triple-negative breast cancer. About 216 adults with early-stage or locally advanced disease will receive either toripalimab plus one of two chem…

This study tests whether a new drug, trastuzumab-rezetecan, works better than the current standard T-DXd for shrinking HER2-positive breast tumors before surgery. About 68 women with early or locally advanced breast cancer will receive one of the two drugs for 8 cycles, then have…

This phase 3 trial tests whether the drug toripalimab, given after surgery, can help prevent esophageal cancer from returning in high-risk patients. About 435 adults who had surgery after chemo-immunotherapy will either receive toripalimab or just be watched. The main goal is to …

This study looks at how well the drug glofitamab works for people with a type of blood cancer called diffuse large B-cell lymphoma that did not respond to or came back quickly after initial treatment. About 20 adults will be treated as part of their normal care, and researchers w…

This study tests a combination of radiation therapy and two drugs (tislelizumab and anlotinib) for people with liver cancer that has spread into the main blood vessel of the liver (portal vein tumor thrombus). The goal is to shrink tumors and improve survival. About 27 adults wil…

This study tests a daily pill called lisaftoclax (APG-2575) in 75 adults with slow-growing lymphomas (CLL, WM, or MZL) who cannot take or have stopped responding to standard treatments. The goal is to see if the drug is safe and can shrink or control the cancer. Participants take…

This study tests whether a combination of two anti-nausea drugs (rolapitant and palonosetron) can prevent vomiting and severe nausea in lung cancer patients receiving both chemotherapy and radiation. About 238 adults with lung cancer will take part. The goal is to find a better w…

This study aims to develop an artificial intelligence system that helps doctors choose the best treatment for each person with esophageal cancer. Researchers will collect data from 7,000 patients, including medical images and tissue samples, to train the AI. The goal is to predic…