Henan Cancer Hospital

This study tests whether giving a combination of three drugs (nab-paclitaxel, carboplatin, and Camrelizumab) before surgery can eliminate all signs of cancer in people with early-stage triple-negative breast cancer. About 64 participants will receive the treatment and then have s…

This study tests whether adding the drug QL1706 to standard chemotherapy can eliminate more cancer before surgery in people with early HR+/HER2- breast cancer. About 238 participants will receive either the combination or chemo alone for 6 cycles, then have surgery. After surgery…

This study tests a new treatment called BioTTT001, a modified virus designed to attack cancer cells, in people with advanced non-small cell lung cancer that has spread to the lining of the brain and spinal cord (meningeal metastasis). The trial aims to find a safe dose and see if…

This study tests a combination of two drugs, utidelone and bevacizumab, in people with advanced HER-2 negative breast cancer who have already tried at least two other treatments. The goal is to see if the combination can slow or stop the cancer from growing. About 79 women aged 1…

This study tests a drug called toripalimab (an immunotherapy) combined with chemotherapy in people with advanced HER2-negative breast cancer that has come back or spread. The goal is to see if the combination can shrink tumors or slow the disease. About 92 adults whose cancer did…

This study tests an experimental drug called SHR-A1811 in people with advanced breast cancer that has spread to the brain. The cancer must have a protein called HER2 (either high or low levels). The goal is to see if the drug can shrink brain tumors and control the disease. About…

This study is testing a combination of two drugs, zanubrutinib and rituximab, as a first treatment for people with marginal zone lymphoma, a slow-growing blood cancer. About 30 adults will take part to see how well the combo shrinks tumors and keeps the disease from progressing. …

This early-phase study tests a new cell therapy called RE002 for people with advanced solid tumors that have a specific genetic mutation (KRAS G12D). The treatment uses the patient's own immune cells, modified to recognize and attack the cancer. The study aims to see if the treat…

This study is testing whether adding a drug called fruquintinib to standard chemotherapy and trastuzumab can help control advanced HER2-positive stomach or gastroesophageal junction cancer. It is for people who have not had prior treatment for their metastatic disease. The goal i…

This study tests a new treatment for lung cancer that has spread to the lining of the brain (meningeal metastasis). The treatment uses tiny particles made from the patient's own tumor cells to deliver the chemotherapy drug methotrexate directly into the spinal fluid. The goal is …

This study tests a drug called efbemalenograstim alfa to prevent febrile neutropenia (a dangerous drop in white blood cells with fever) in people with solid tumors getting chemotherapy. About 1,076 participants will receive the drug either as a first-time prevention or after a pr…

This study looks at whether a special test that measures T cells in the blood can predict how well a combination of immunotherapy and chemotherapy works for people with advanced small cell lung cancer. Researchers will enroll 40 patients who have not had treatment before. The goa…