Harmony Biosciences Management, Inc.

This study looked at the long-term safety and effectiveness of the drug pitolisant for adults with idiopathic hypersomnia, a condition causing excessive daytime sleepiness. All 119 participants had completed a prior study of the same drug. Researchers measured sleepiness and othe…

This study tested a medication called pitolisant to see if it could safely reduce severe daytime sleepiness in people with Prader-Willi syndrome, a genetic condition. 65 participants aged 6 to 65 took either the drug or a placebo for 11 weeks. The main goal was to measure changes…

This study tested a new delayed-release form of the drug pitolisant (called HBS-201) in 46 adults with narcolepsy. The main goal was to see if starting at a full therapeutic dose is tolerable, meaning few people stop treatment due to side effects. Researchers tracked how many par…

This study tested a gel called ZYN002, applied to the skin, in 20 children aged 4 to 17 with 22q11.2 deletion syndrome. The goal was to see if the gel is safe and tolerable over 38 weeks. Researchers also looked at whether it could improve challenging behaviors. The gel is a form…

This study looked at how a CBD gel (ZYN002) affects the way the body processes other drugs. Twenty-nine healthy adults took the gel along with several common medications to see if it changed drug levels in the blood. The goal was to understand potential interactions, not to treat…