Goethe University

This study tests a drug called isatuximab in 40 adults with a rare and aggressive blood cancer (T-cell acute lymphoblastic leukemia, or T-ALL) that has returned or not responded to standard treatment. The drug targets a protein (CD38) on the cancer cells to help the immune system…

This study tests whether a natural compound called urolithin A can improve the immune response in people with solid tumors (like lung cancer or melanoma) who are starting immunotherapy. About 45 participants will receive either urolithin A or a placebo alongside their standard ca…

This study is a large registry that collects medical information and biological samples from 10,000 adults with acute lymphoblastic leukemia (ALL) and similar blood cancers. The goal is to track how patients are diagnosed, treated, and how they fare over time, including survival …

This study is observing 100 adults with major depression who are already receiving transcranial magnetic stimulation (TMS) as part of their regular care. Researchers want to see if brain scans and symptom patterns can predict who will respond to TMS. They will track how symptoms …

This study looks at how robot-assisted bladder removal surgery affects blood loss, pain, and the need for blood transfusions. Researchers will follow 60 patients who are scheduled for this surgery. The goal is to gather information, not to test a new treatment.