Global Coalition For Adaptive Research

This study aims to find safe and effective medications to help control symptoms of Post-Traumatic Stress Disorder (PTSD). It will enroll 800 active-duty service members and veterans to test several different drugs against a placebo over 12 weeks. The trial uses a flexible design …

This study is testing whether a medication called daridorexant, which is currently used for insomnia, can help control symptoms of Post-Traumatic Stress Disorder (PTSD). It will involve 200 active-duty service members and veterans. Participants will be randomly assigned to receiv…

This study aims to find out if the medication fluoxetine is safe and effective at reducing symptoms of Post-Traumatic Stress Disorder (PTSD). It will involve 200 active-duty service members and veterans who have PTSD. Participants will be randomly assigned to receive either fluox…

This large international trial is testing several different treatments for glioblastoma (GBM), a fast-growing brain cancer. It aims to find which therapies work best for newly diagnosed patients and for those whose cancer has returned. The trial uses a smart, flexible design to q…