General University Hospital, Prague

Researchers are testing whether an intensive lifestyle program built on cognitive behavioral therapy and mindfulness can improve liver health in people with non-alcoholic fatty liver disease and metabolic syndrome. About 100 participants receive individually tailored coaching fro…

This study is testing whether a 12-week physiotherapy and exercise program can improve physical fitness and quality of life in adults with Fabry disease. Fifteen participants will do regular exercise sessions using body weight, resistance bands, and increased daily activity. The …

This study tests whether real-time visual feedback from the SpiroGym app helps people with Parkinson's disease perform breathing muscle exercises more effectively. Thirty participants will do the exercises with and without the app's feedback, and researchers will measure muscle a…

This study tests whether an 8-week very-low-calorie diet (600-800 kcal/day) can alter bone marrow fat, bone health, and stem cell function in obese premenopausal women. Researchers will use MRI and biopsies to measure changes in vertebral bone marrow fat and the behavior of bone …

This study looks at whether testing for HPV DNA from a cervical swab or a blood sample can help find cervical cancer that has come back after radiotherapy. Researchers will follow 120 patients for two years after treatment, collecting samples at regular visits. The goal is to see…

This study follows 300 women aged 18–40 with severe cervical precancer (CIN 2 or 3) to see how often these lesions regress on their own or after surgery. Researchers will track HPV and Pap test results to identify factors that predict healing. The goal is to create a model that h…