Fondazione Irccs Istituto Nazionale Dei Tumori, Milano

This trial is testing a new combination of chemotherapy drugs for people with a specific type of advanced colorectal cancer that has spread. The treatment is designed for patients whose tumors have certain genetic features. The main goals are to find the safest dose and see if th…

This study is testing if women with certain aggressive breast cancers (HER2-positive or Triple-negative) who have an excellent response to initial drug therapy can safely skip standard follow-up treatments. One group will skip surgery, and another will skip radiation. The goal is…

This study is for men whose prostate cancer has spread to a few other spots in the body but is still sensitive to hormone-blocking drugs. It aims to see if adding a direct treatment to the prostate itself—like surgery or radiation—on top of standard drug therapy is better at keep…

This study aims to create a better test to predict which people with Familial Adenomatous Polyposis (FAP) are at highest risk for developing duodenal cancer. Researchers will analyze data from 300 FAP patients who have had multiple endoscopies to develop and validate new risk mod…

This study is creating a large international registry to collect information on patients with a very rare cancer called Epithelioid Hemangioendothelioma (EHE). It aims to understand how the disease behaves over time, identify factors that predict outcomes, and see how well curren…

This study aims to better understand a very rare cancer called epithelioid haemangioendothelioma (EHE). Researchers will observe 50 patients to collect detailed information on how the disease presents, its natural course, and how patients respond to treatments. The main goal is t…

This study aims to understand if the bacteria in a patient's mouth influence how well radiation therapy works for head and neck cancer and how severe the side effects are. Researchers will collect saliva samples from about 100 patients before, during, and after their radiation tr…