Dr. Inge Winter

This study is testing if starting a stronger antipsychotic medication called clozapine earlier is better for people with schizophrenia. It's for adults whose first medication didn't work well. Researchers will compare the effects of this early, intensified treatment to the usual …

This large study is testing if using stronger, third-line psychiatric medications right after a first treatment fails works better than the standard second-step approach. It involves over 1,200 adults with schizophrenia, major depression, or bipolar depression who did not get bet…

This study is testing if a more intense medication approach works better for people with bipolar depression when their first treatment fails. It will compare a stronger, three-drug combination given early against the usual second-choice treatment. The goal is to see if this faste…

This study is for adults with major depression whose first antidepressant didn't work well enough. It compares two next steps: switching to a different standard pill (usual care) versus quickly adding a stronger treatment, esketamine (a nasal spray or IV infusion), to a pill. The…