Debiopharm International Sa

This study tests a new drug, Debio 0123, combined with standard chemotherapy (temozolomide) and sometimes radiation for adults with glioblastoma, a fast-growing brain tumor. The goal is to find the safest dose and see if the combination helps people live longer. About 116 partici…

This study tests a new drug called Debio 1562M in people with acute myeloid leukemia (AML) that has come back or not responded to other treatments. The first part finds a safe dose, and the second part checks if the drug can shrink or control the cancer. About 134 participants wi…

This early-phase study tests a new drug called lunresertib, alone or with other drugs, in people with advanced solid tumors that have stopped responding to standard treatments. The main goals are to check safety, find the best dose, and see if the drug can shrink tumors. About 46…

This study tests a new long-acting medication called Debio 4126 for people with acromegaly, a condition where the body makes too much growth hormone. The drug is given every 12 weeks and aims to keep hormone levels normal. About 119 adults who are already on similar treatments wi…

This early-stage study is testing an experimental drug called Debio 1453P in 88 healthy adults aged 18 to 55. The goal is to check if the drug is safe and how the body handles it at different doses. Participants will receive either the drug or a placebo. This study does not aim t…