Compass Pathways
Clinical trials sponsored by Compass Pathways, explained in plain language.
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Magic mushroom compound tested as breakthrough treatment for Hardest-to-Treat depression
Disease control OngoingThis large international study is testing whether psilocybin (the active compound in 'magic mushrooms'), given with psychological support, can help people with severe depression that hasn't improved with standard antidepressant medications. The trial involves 572 adults who have …
Phase: PHASE3 • Sponsor: COMPASS Pathways • Aim: Disease control
Last updated Apr 04, 2026 07:06 UTC
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Magic mushroom compound tested as potential breakthrough for severe depression
Disease control OngoingThis large, late-stage trial is testing whether a single dose of a psilocybin-based therapy (COMP360), given with psychological support, can reduce symptoms in people with treatment-resistant depression. About 255 participants will be randomly assigned to receive either the activ…
Phase: PHASE3 • Sponsor: COMPASS Pathways • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC