Compass Pathways
Clinical trials sponsored by Compass Pathways, explained in plain language.
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Magic mushroom compound tested as breakthrough for Hard-to-Treat depression
Disease control OngoingThis large Phase 3 trial is testing whether two doses of a psilocybin-based therapy (COMP360), given with psychological support, can help adults with severe treatment-resistant depression. The study will compare different dose strengths to see which works best at reducing depress…
Phase: PHASE3 • Sponsor: COMPASS Pathways • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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Magic mushroom compound tested as potential breakthrough for severe depression
Disease control OngoingThis large, late-stage trial is testing whether a single dose of a psilocybin-based therapy (COMP360), given with psychological support, can reduce symptoms in people with treatment-resistant depression. About 255 participants will be randomly assigned to receive either the activ…
Phase: PHASE3 • Sponsor: COMPASS Pathways • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC