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Compass Pathways

Clinical trials sponsored by Compass Pathways, explained in plain language.

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  • Magic mushroom drug takes on stubborn depression in major trial

    Symptom relief Ongoing

    This study tests whether a single dose of COMP360, a psilocybin-based drug, can ease depression in people who haven't gotten better with other treatments. About 255 adults with moderate-to-severe depression will receive either the drug or a placebo. Researchers will track changes…

    Phase: PHASE3 • Sponsor: COMPASS Pathways • Aim: Symptom relief

    Last updated May 13, 2026 16:03 UTC

  • Magic mushroom compound takes on tough depression in major trial

    Symptom relief Ongoing

    This study tests whether two doses of COMP360 (a form of psilocybin) can safely ease depression in 572 adults whose depression hasn't improved with standard treatments. Participants receive either a high or low dose, and researchers track mood changes and daily functioning over t…

    Phase: PHASE3 • Sponsor: COMPASS Pathways • Aim: Symptom relief

    Last updated May 12, 2026 13:41 UTC

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