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Compass Pathways

Clinical trials sponsored by Compass Pathways, explained in plain language.

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  • Magic mushroom compound takes on depression in major trial

    Symptom relief Ongoing

    This study tests a drug called COMP360 (a form of psilocybin, the active ingredient in magic mushrooms) in people with depression that hasn't improved with other treatments. About 572 adults will receive either a high or low dose, and researchers will measure changes in mood and …

    Phase: PHASE3 • Sponsor: COMPASS Pathways • Aim: Symptom relief

    Last updated Jun 27, 2026 08:10 UTC

  • Magic mushroom compound takes on tough depression in major trial

    Symptom relief Ongoing

    This phase 3 trial tests whether a single dose of COMP360 psilocybin, given under supportive conditions, can safely reduce depression symptoms in 255 adults with treatment-resistant depression. Participants are randomly assigned to receive either the drug or a placebo, and their …

    Phase: PHASE3 • Sponsor: COMPASS Pathways • Aim: Symptom relief

    Last updated Jun 27, 2026 08:05 UTC

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