Children's National Research Institute

This early-phase trial tests whether immune cells (T cells) grown in a lab from a donor can safely prevent or treat seven different viruses in people who have had a bone marrow transplant. About 32 participants will receive these cells either as a preventive measure or to treat a…

This early-phase study tests a new treatment for children and young adults with high-risk solid tumors that have not responded to standard therapy. The approach uses a patient's own immune cells, trained to recognize multiple cancer targets, to attack the tumor. The main goal is …

This study tests whether a medicine called Amicar can reduce blood loss in children aged 2 to 36 months who need skull surgery for a condition called craniosynostosis. The goal is to see if it lowers the need for blood transfusions during and after the operation. The study involv…

This study tests whether a new educational tool helps medical learners get more out of their pediatric palliative care rotation. About 30 adult learners will use the tool during their rotation and then answer survey questions about their experience. Researchers will compare their…

This study looks at the unmet palliative care needs of children with rare diseases and their family caregivers. Researchers will test a program called FACE-Rare to see if it helps families prepare for medical decisions and improves quality of life. About 480 children and their ca…

This study looks at how a cognitive behavioral program designed to improve flexibility in teens with autism (ages 14-18) may change the way they learn and how their brains work. Researchers will use brain scans and thinking tests to see if the program helps with learning and dail…