Children's Hospital Of Orange County

This study tests whether peppermint oil capsules can ease bladder and bowel symptoms in children aged 8-17 who haven't improved with standard behavioral therapy. For 8 weeks, 30 participants will take peppermint oil three times daily. Researchers will compare symptom questionnair…

This study follows a small group of people with a rare, late-onset form of TPP1 deficiency (also called CLN2 disease) to learn how their symptoms change over time. Researchers will use tests like brain scans, eye exams, and movement assessments to gather information. The goal is …

This study follows 30 people with mucopolysaccharidoses (MPS) over 3 years to see how their heart and arteries change over time. Researchers use painless ultrasound scans and blood tests to measure artery thickness, stiffness, and signs of inflammation. The goal is to better unde…