Children's Hospital Medical Center, Cincinnati

This study looked at how effective the Rotarix vaccine is at preventing severe rotavirus infections in young children. Researchers enrolled 362 children under 6 years old who came to the hospital with vomiting and diarrhea. They compared those who tested positive for rotavirus wi…

This study tested whether smartphone reminders, educational tips, and personalized feedback could help children with epilepsy take their anti-seizure medication as prescribed. About 268 children aged 2 to 12 years who were recently diagnosed with epilepsy took part. The goal was …

This study tested a program that uses technology to help teenagers with asthma remember to take their daily inhaler medication. 72 teens with moderate to severe asthma participated. The program used electronic monitors and step-by-step support to improve medication adherence, com…

This study tested a drug called dupilumab in 41 people aged 12 to 70 with eosinophilic gastritis, a condition where too many immune cells cause stomach inflammation. Participants received either dupilumab or a placebo injection every two weeks for 12 weeks, with an option to cont…

This study looked at whether tofacitinib, a drug that calms the immune system, is safe and helpful for young adults aged 18 to 45 with moderate to severe lupus skin disease. Thirteen participants took the drug for up to 76 weeks. The main goal was to measure how the body processe…

This study tested whether a natural sugar called 2'-fucosyllactose (2FL) is safe and helpful for people receiving a bone marrow transplant. The goal was to see if it could improve gut health, reduce harmful bacteria, and lower the risk of infections and graft-versus-host disease.…

This study tested a program called HALO for children aged 6-12 whose mothers had weight-loss surgery. The program helped kids learn healthier eating and activity habits. 35 families took part to see if the program could help children maintain a healthy weight.

This study looked at how to improve testing for sexually transmitted infections (STIs) like gonorrhea and chlamydia in teenagers visiting emergency departments. Researchers compared two methods: testing only teens with certain risk factors versus offering testing to everyone. The…

This study tested a special toothpaste containing tacrolimus to help manage painful mouth sores caused by chronic graft vs. host disease (cGVHD) after a stem cell transplant. Seven patients under 40 years old used the toothpaste alongside their regular medicines. The goal was to …

This small pilot study tested whether custom 3D-printed masks could help children with sleep apnea use their CPAP machines more comfortably. Fifteen children had their faces scanned to create a personalized mask, which they used for about six months. Researchers measured how ofte…

This study looked at 19 premature babies with a chronic lung condition called bronchopulmonary dysplasia (BPD). Doctors often use diuretics (water pills) to help these babies breathe, but it's unclear who truly benefits. The researchers tested a personalized approach called an N-…

This study tested a new program designed to help teens and young adults (ages 15-24) with cancer take their oral chemotherapy or preventive medications as prescribed. 70 participants were randomly assigned to either the tailored program or standard care. The main goal was to see …

This study tested a remote, simulation-based training program for 133 emergency medical services (EMS) clinicians to improve their skills in pediatric procedures like breathing support and IV access. Participants practiced on mannequins and submitted videos for scoring. The goal …

This study tested a program called GET2HOME, which uses telehealth to support children with complex chronic conditions and their families after leaving the hospital. Over 600 children participated to see if the program reduces unplanned hospital visits and improves quality of lif…

This study looked at how getting more sleep at the right time of day affects what teenagers eat. Researchers compared teens who are natural morning people (morning larks) with those who are night owls. The goal is to understand why sleep helps some teens eat less and make healthi…

This study involved 8 children and teens with cystic fibrosis who had a history of MRSA infection and were receiving the antibiotic ceftaroline. Researchers measured drug levels in the blood to see if current dosing recommendations work well for this group. The goal was to gather…