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Celalettin Topbaş

Clinical trials sponsored by Celalettin Topbaş, explained in plain language.

Could a cold rinse and diabetes drug soothe root canal pain?

Symptom relief Completed

This study tested whether rinsing the tooth with cold saline (cryotherapy) or placing metformin (a diabetes drug) inside the tooth can reduce pain after root canal treatment. 80 adults with infected lower premolars were randomly assigned to receive one of four treatments. Pain wa…

Sponsor: Celalettin Topbaş • Aim: Symptom relief

Last updated Sep 18, 2026 00:00 UTC