Blueprint Medicines Corporation

This study tested a drug called avapritinib in 107 people with advanced systemic mastocytosis, a rare and serious blood disorder. The drug targets a specific genetic change that drives the disease. Results showed that many patients had their tumors shrink or symptoms improve, but…

This study tested a drug called avapritinib in 29 children aged 2 to 18 with advanced solid tumors that have specific gene changes (KIT or PDGFRA). The goal was to see if the drug is safe and can shrink tumors. Since these children had no other treatment options, the study aimed …

This study tested a new drug called BLU-808 in 21 adults with ragweed allergies. Participants were exposed to ragweed pollen in a special chamber to see if the drug safely reduces allergy symptoms like sneezing and itchy eyes. The goal was to check safety and how well the drug wo…

This study looked at how a drug called elenestinib changes the way the body processes midazolam (a sedative) and a common birth control pill. Twenty healthy adult women took these drugs with and without elenestinib, and had blood tests to measure drug levels. The goal was to unde…