Bayer

This study tests a single injection of AB-1005 gene therapy directly into the brain for Japanese adults with moderate Parkinson's disease. The goal is to see if it is safe and can improve daily movement and reduce 'off' time. Eight participants will be followed for 18 months.

This study follows 40 children aged 7 to 12 with hemophilia A who are already prescribed damoctocog alfa pegol, a medicine that replaces missing clotting factor. Researchers will collect information from routine care—like bleeding episodes and health diaries—over two years to see…

This study looks at how safe and effective Octocog alfa is for treating bleeding episodes in adults with severe hemophilia A in India. It will follow 33 people who have used Factor VIII before and are getting the drug only when they bleed. The goal is to see how the drug works in…

This study looks at how well darolutamide (a newer drug) plus standard hormone therapy works in Chinese men whose prostate cancer has become resistant to earlier treatment but hasn't spread. About 800 men will take part, and researchers will check if their PSA levels drop very lo…

This study looks at the safety of a drug called finerenone for children and young adults (birth to 18 years) with heart failure and left ventricular systolic dysfunction (LVSD). Participants take finerenone along with their usual heart medications for up to 9 months. The study tr…

This study looks at how well a new hormone-free medicine called elinzanetant works for hot flashes, night sweats, and sleep problems in women going through menopause. About 1,500 women in the U.S. will use a phone app to report their symptoms and quality of life while taking the …

This study follows 50 pregnant women with Chagas disease who have taken or will take nifurtimox during pregnancy. Researchers will track birth defects, pregnancy outcomes, and infant health up to 12 months old. The goal is to collect safety data, not to test a new treatment. Resu…

This study looks at how blood thinners like rivaroxaban are used in children under 2 years old who have blood clots. Researchers will collect information from medical records and insurance claims to see how well these medicines work and if they cause serious bleeding. No extra te…

This study will follow 500 adults in Spain with chronic kidney disease and type 2 diabetes who are taking finerenone. Researchers want to see if a tool called the Klinrisk score, which estimates kidney disease progression, improves after 2 years of treatment. The study will colle…

This early-stage study looks at whether it is safe to take nitroglycerin spray together with a new drug called nurandociguat in people with stable coronary artery disease. Both drugs widen blood vessels, so combining them might cause a sudden drop in blood pressure. The study wil…

This study looks at whether a digital tool called Luscii is practical and acceptable for people with transthyretin amyloid cardiomyopathy (ATTR-CM), a rare heart condition. About 60 adults in Austria, Germany, and Italy will use the app at home to share health information with th…