Assistance Publique Hopitaux De Marseille

This study tested if using a special monitor to check oxygen levels in a patient's large vein during surgery helps doctors give the right amount of IV fluids. The goal was to see if this approach leads to fewer complications after major abdominal surgery. It involved 220 patients…

This study tested whether lupus nephritis patients who have been in stable remission for at least a year could safely stop their maintenance immunosuppressive drugs after two years of treatment. One hundred participants were randomly assigned to either continue their current immu…

This study compared two blood-filtering techniques (plasma exchange and immunoadsorption) to see which one removes harmful antibodies faster in patients with severe autoimmune kidney failure or lung bleeding. The goal was to quickly reduce these damaging antibodies while waiting …

This study tested a new blood test to see if it could accurately diagnose food allergies in children. Researchers compared the blood test results to the current standard method, which involves feeding children small amounts of the suspected food under medical supervision. The goa…

This study tested whether a low, continuous dose of ketamine could reduce the amount of strong opioid painkillers needed by patients with severe traumatic injuries. It involved 140 adults who had injuries in at least two major body regions. The goal was to see if ketamine could c…

This study tested if a safe, personalized exercise program could help children and teenagers with advanced cancer. Researchers carefully measured how much activity was tolerable for these young patients, aiming to see if it could ease symptoms like pain and fatigue. The goal was …

This study tested whether virtual reality therapy could prevent anxiety, depression, and PTSD in lung transplant patients recovering in the intensive care unit. Patients on the transplant waiting list used VR headsets to gradually experience simulated ICU sounds and environments,…

This study aimed to understand the lasting health problems adults can face after surviving a severe case of malaria. Researchers followed 56 adults who were treated for severe malaria to see what issues, like kidney or brain problems, were still present one year later. The goal w…

This study looked at how common muscle loss (called sarcopenia) is in men aged 70 and older who have prostate cancer and are being treated with radiation and hormone therapy. Researchers followed 112 patients to understand the link between cancer treatments and muscle weakening. …

This study aimed to find new markers in MRI brain, spinal cord, and muscle scans that could help doctors diagnose ALS earlier and track how the disease changes over time. Researchers compared advanced MRI results from 22 ALS patients with standard clinical tests at three points o…

This study aimed to develop a better way to measure how active lupus is in a patient and predict its future course. Researchers analyzed blood samples from 80 adults with lupus to look for patterns in gene activity. The goal was to create a blood test score that could help doctor…

This study aimed to understand why pneumonia often returns in COVID-19 patients on ventilators despite antibiotic treatment. Researchers measured how well two common antibiotics (piperacillin and tazobactam) moved from the bloodstream into the lung tissue of 34 critically ill pat…

This study aimed to understand how systemic lupus erythematosus (SLE) affects patients' relationships and daily life with their partners. Researchers surveyed 100 patients and conducted in-depth interviews with 40 patients and 20 spouses. The goal was to gather insights to improv…

This study aimed to learn about tiny particles in the blood called microparticles in people with advanced colorectal cancer that has spread to the abdominal lining. Researchers compared these particles in 41 patients with and without this specific cancer spread to see if they cou…

This study tested new 3D MRI scanning methods to create moving images of how pelvic organs shift and deform during activities. Researchers enrolled 50 adult women to capture these detailed movements, aiming to better understand pelvic floor disorders that affect many women's qual…

This study aimed to see if researchers could successfully create and store a collection of 3D 'mini-organ' models, called organoids, grown from liver cancer tissue. The organoids were grown from tissue samples donated by 48 patients with liver tumors. If successful, this biobank …

This study used a powerful MRI scanner to look for subtle changes in the brains of people with a specific sleep disorder called REM sleep behavior disorder (RBD). Many people with this sleep disorder later develop Parkinson's disease. Researchers compared brain scans from 15 peop…

This study aimed to better understand how Chronic Obstructive Pulmonary Disease (COPD) affects blood vessels in the lungs. Researchers used MRI scans to measure blood flow in the lungs of 30 people with COPD, both at rest and after light exercise. The goal was to gather informati…