Abbvie

This study tested an experimental drug called telisotuzumab vedotin for people with a certain type of advanced lung cancer (non-squamous non-small cell lung cancer) that has a specific gene change called MET amplification. The goal was to see if the drug could shrink tumors. The …

This study tested whether two drugs, venetoclax and azacitidine, could help people with acute myeloid leukemia (AML) live longer after a stem cell transplant. The trial included adults and teenagers who had a stem cell transplant or were planning one. The goal was to see if this …

This early-stage study tested an experimental drug called ABBV-303, alone or with another drug (budigalimab), in adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check safety and find the right dose. The study was termin…

This study looked at the long-term safety of an experimental drug called CVL-865 for adults whose focal seizures (seizures starting in one part of the brain) were not controlled by other medications. About 105 people who had finished a previous trial were enrolled. The study was …

This study tested two experimental drugs, budigalimab and ABBV-382, in people with HIV who were on stable antiretroviral therapy (ART). Participants stopped their regular HIV pills under close monitoring to see if the new drugs could keep the virus under control. About 160 adults…

This study tested a liquid medicine called paricalcitol in children aged 0 to 9 with severe kidney failure who are on dialysis. The goal was to see if it safely lowers high parathyroid hormone levels, a common complication. The study was stopped early after enrolling only 2 parti…

This study tested the drug cariprazine (Vraylar) for adults with schizophrenia in Japan and Taiwan. About 250 people were planned, but only 34 enrolled before the study was stopped early. Participants took either cariprazine or a placebo for 6 weeks, then could continue on caripr…

This study tested whether BOTOX injections can prevent migraine headaches in adults who have 6 to 14 migraine days per month (episodic migraine). About 775 participants received either BOTOX or placebo injections into their muscles twice, 12 weeks apart. The study was terminated …

This study tested a new medicine called fosigotifator for adults with major depression. About 20 people were planned to take either the drug or a placebo to see if it was safe and helped symptoms. The study was stopped early, so results are limited.

This study tested a drug called darigabat to see if it could help people with panic disorder have fewer panic attacks. About 80 adults with frequent panic attacks were to receive either the drug or a placebo. The trial was stopped early, so results are limited.

This study tested a drug called CVL-871 to see if it is safe and can reduce apathy in people with dementia. The trial included 41 participants with mild to moderate dementia and clinically significant apathy. The study was terminated early, and results focus on safety and changes…

This study looked at how safe ABBV-1088 is and how the body processes it in healthy adults from Western, Han-Chinese, and Japanese backgrounds. It also checked for interactions with another drug, itraconazole. The study was terminated early, so results are limited.

This study followed pregnant women who had taken elagolix (brand names Orilissa or Oriahnn) for endometriosis or uterine fibroids, comparing them to similar pregnant women who had not taken the drug. The goal was to see if the drug affected pregnancy outcomes, such as birth defec…