3d Medicines (sichuan) Co., Ltd.

This study tests a drug called Envafolimab in people with advanced solid tumors that have a high number of genetic mutations (TMB-H). The goal is to see how well the drug shrinks tumors and to find the best way to measure mutation levels. About 126 adults who have tried at least …

This study is testing whether combining two drugs, envafolimab and lenvatinib, can shrink tumors in people with advanced solid tumors (like lung, kidney, or liver cancer) who have run out of standard options. About 170 adults will receive the combination to find the best dose and…

This study tests a drug called KN035 in people with advanced solid tumors that have a specific genetic feature (dMMR or MSI-H). These tumors often don't respond well to standard treatments. The goal is to see if KN035 can shrink tumors and control the disease. About 200 participa…

This study tests whether adding the drug envafolimab to standard chemotherapy helps people with stage III non-small cell lung cancer that can be removed with surgery. About 390 participants will receive either envafolimab plus chemo or a placebo plus chemo before and after surger…

This study tests a drug called envafolimab, given alone or with another drug called lenvatinib, in people with advanced endometrial cancer that has not responded to standard chemotherapy. The goal is to see if the treatment can shrink tumors. About 108 participants will take part…