XEROSTOMIA
Clinical trials for XEROSTOMIA explained in plain language.
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Whitening gel may freshen breath and moisturize mouth
Symptom relief OngoingThis study tests whether a whitening serum (Crest Daily Whitening Serum) can reduce dry mouth and bad breath in 27 adults who already have these issues. Participants use the product for one week and report changes in dryness and breath odor. The goal is symptom relief, not a cure…
Matched conditions: XEROSTOMIA
Phase: NA • Sponsor: Tufts University • Aim: Symptom relief
Last updated May 26, 2026 11:14 UTC
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Toothpaste ingredient may bring relief to dry mouth sufferers
Symptom relief OngoingThis study tests whether a toothpaste containing arginine can improve dry mouth (xerostomia) by changing the acidity of saliva and the types of bacteria in the mouth. About 70 adults who take medications that cause dry mouth will use the toothpaste for 12 weeks. Researchers will …
Matched conditions: XEROSTOMIA
Phase: PHASE3 • Sponsor: Tufts University • Aim: Symptom relief
Last updated May 22, 2026 14:01 UTC
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Stem cells aim to quench Radiation-Induced dry mouth
Symptom relief OngoingThis early-phase study tests whether injecting a person's own bone marrow stem cells into their salivary glands can safely reduce dry mouth caused by radiation therapy for head and neck cancer. About 23 adults who finished radiation at least 2 years ago and have no active cancer …
Matched conditions: XEROSTOMIA
Phase: PHASE1 • Sponsor: University of Wisconsin, Madison • Aim: Symptom relief
Last updated May 14, 2026 12:06 UTC
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New MRI technique aims to spare throat cancer patients from lifelong dry mouth
Symptom relief TerminatedThis study was designed to see if using MRI scans to guide radiation therapy can better protect the salivary ducts and reduce dry mouth in people with oropharynx cancer. Dry mouth is a common and lasting side effect of radiation. The plan was to compare patient-reported dry mouth…
Matched conditions: XEROSTOMIA
Phase: NA • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 13, 2026 15:59 UTC
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Radiation's hidden toll: new study tracks oral health in cancer survivors
Knowledge-focused OngoingThis study follows 100 head and neck cancer patients before and after radiotherapy to see how it affects their teeth, gums, and saliva over time. Researchers measure gum health and ask about quality of life. The goal is to better understand long-term mouth problems from radiation…
Matched conditions: XEROSTOMIA
Sponsor: Ain Shams University • Aim: Knowledge-focused
Last updated May 26, 2026 11:11 UTC