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Toothpaste breakthrough: could arginine ease dry mouth for millions?

NCT ID NCT06365047

First seen Nov 01, 2025 · Last updated Jun 11, 2026 · Updated 34 times

Summary

This study tests whether a toothpaste with arginine can improve dry mouth (xerostomia) by changing saliva acidity and mouth bacteria. About 70 adults with dry mouth caused by medications will use the toothpaste for 3 months. Researchers will measure saliva pH and oral microbiome changes to see if the toothpaste helps.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Tufts University School of Dental Medicine

    Boston, Massachusetts, 02111, United States

Conditions

The condition(s) this trial relates to.

Xerostomia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.