Toothpaste breakthrough: could arginine ease dry mouth for millions?

NCT ID NCT06365047

First seen Nov 01, 2025 · Last updated Jun 11, 2026 · Updated 34 times

Summary

This study tests whether a toothpaste with arginine can improve dry mouth (xerostomia) by changing saliva acidity and mouth bacteria. About 70 adults with dry mouth caused by medications will use the toothpaste for 3 months. Researchers will measure saliva pH and oral microbiome changes to see if the toothpaste helps.

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Contacts and locations

Locations

  • Tufts University School of Dental Medicine

    Boston, Massachusetts, 02111, United States

Conditions

Explore the condition pages connected to this study.