WRINKLE
Clinical trials for WRINKLE explained in plain language.
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New filler shows promise for dark Under-Eye circles
Symptom relief CompletedThis study tested whether a gel filler called RHA Redensity Eye can safely improve moderate to severe under-eye hollows (sunken areas). 248 adults were randomly assigned to receive the filler or no treatment. The main goal was to see if the filler reduced hollow severity after 12…
Matched conditions: WRINKLE
Phase: NA • Sponsor: Teoxane SA • Aim: Symptom relief
Last updated May 26, 2026 05:54 UTC
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Anti-Aging creams put to the test: do they really work?
Symptom relief CompletedThis study tested four topical products to see if they could improve facial skin longevity and reduce wrinkles over eight weeks. A total of 132 healthy adults aged 40 to 65 used the products and provided feedback through questionnaires and skin imaging. The main goal was to measu…
Matched conditions: WRINKLE
Phase: NA • Sponsor: Amazentis SA • Aim: Symptom relief
Last updated May 22, 2026 14:04 UTC
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New study pits two wrinkle fillers Head-to-Head for smile lines
Symptom relief CompletedThis study tested two hyaluronic acid fillers, Defyne and RHA3, to see which works better for smile lines (nasolabial folds). Fifteen adults received one filler on each side of their face, with optional touch-ups after 4 weeks. Researchers used ultrasound and 3D imaging to compar…
Matched conditions: WRINKLE
Phase: NA • Sponsor: Galderma R&D • Aim: Symptom relief
Last updated May 20, 2026 11:54 UTC
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New device uses tiny skin plugs to smooth wrinkles
Symptom relief CompletedThis study tested a device that removes tiny cores of skin (about the width of a few hairs) to trigger the body's natural repair process, creating new collagen and elastin. Forty-five adults with moderate-to-severe wrinkles and skin looseness around the cheeks, mouth, and jawline…
Matched conditions: WRINKLE
Phase: NA • Sponsor: Cytrellis Biosystems, Inc. • Aim: Symptom relief
Last updated May 14, 2026 12:02 UTC
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New device promises smoother skin on face and neck
Symptom relief CompletedThis study tested a device called BTL-785F to see if it can improve skin quality and texture on the face and neck. Thirty-nine healthy adults received three treatments and were followed for three months. The main goal was to check for visible skin improvement using photos and a s…
Matched conditions: WRINKLE
Phase: NA • Sponsor: BTL Industries Ltd. • Aim: Symptom relief
Last updated May 04, 2026 16:18 UTC