WOUND HEAL

This early-stage trial tests a topical treatment called Ev.FV in 20 people with dystrophic epidermolysis bullosa, a genetic condition causing fragile, blistering skin. The treatment uses tiny particles from cells to try to speed wound healing. Researchers will measure wound closu…

This trial tests whether a natural ointment called Xiang Lei Ointment can help heal diabetic ulcers better than standard care alone. The ointment aims to reduce inflammation and promote wound repair. The study will enroll 56 adults with diabetes and a foot or leg ulcer that is in…

This study tests whether a negative pressure wound therapy (NPWT) device, placed over the surgical incision, can reduce infections and other wound complications compared to standard dressings in people with severe leg fractures. The trial will enroll 352 patients with high-risk t…

This study tests guselkumab (Tremfya), a drug already used for psoriasis, in 17 adults with pyoderma gangrenosum—a rare disease that leads to painful, hard-to-heal skin ulcers. Participants receive injections every 4 weeks for 28 weeks. Researchers will check if ulcers heal compl…

This study tests whether a special dressing called EDX110, when added to standard care, helps diabetic foot ulcers heal faster and more completely. About 298 adults with a non-healing foot ulcer will be randomly assigned to receive either standard care alone or standard care plus…

This study tests whether a gel called TR987, used with standard wound care, helps heal chronic leg ulcers caused by poor blood flow. About 312 adults with a leg ulcer between 2 and 12 cm² will receive either the gel plus standard care or standard care alone. The main goal is to s…

This pilot study tests whether a special gel containing hyaluronic acid and octenidine can improve early healing after non-surgical gum treatment for periodontitis. About 26 adults with advanced gum disease will receive either standard deep cleaning alone or deep cleaning plus th…

This study tests a device that uses light and magnets (COMS) to help heal chronic leg ulcers. About 122 people with venous leg ulcers will receive either standard care plus COMS or standard care alone. The goal is to see if the device speeds up wound healing and improves quality …

This study tests a wireless, bioelectric bandage called PowerHeal™ on infected wounds. Researchers want to see if it clears infection and helps wounds close better than standard care. About 150 adults with infected traumatic wounds will take part. The bandage is changed regularly…

This study looks at whether medical honey can help heal wounds in intensive care patients better than standard care. About 60 adults with fresh wounds (like pressure sores or cuts) will be randomly assigned to get either honey dressings or usual treatment. The main goal is to see…

This study tests a new type of antibacterial dressing for chronic wounds that have not healed for at least a week. The dressing is made from a special material that breaks down in the body. Researchers want to see if it can safely reduce wound size and improve healing. The study …

This study tests whether a drug called 4-aminopyridine (4-AP) can speed up healing of skin wounds. Researchers will give the drug to 150 healthy adults and measure how quickly small biopsy wounds close. The goal is to find a safe, simple way to help both chronic and acute wounds …

This early study tests whether a new oxygen-delivery system using micro/nanobubbles can safely help heal different types of wounds. About 40 adults with acute or chronic wounds will receive either the oxygen bubbles or a standard saline treatment. Researchers will measure changes…