WHO GRADE IV GLIOMA
Clinical trials for WHO GRADE IV GLIOMA explained in plain language.
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New hope for kids with aggressive brain tumors: targeted drug combo after radiation
Disease control Recruiting nowThis study tests whether adding two different drug combinations after radiation can help children and young adults with high-grade gliomas (including DIPG) live longer. One group receives ribociclib plus everolimus, and another receives ribociclib plus temozolomide, based on the …
Matched conditions: WHO GRADE IV GLIOMA
Phase: PHASE2 • Sponsor: Nationwide Children's Hospital • Aim: Disease control
Last updated May 26, 2026 04:38 UTC
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New hope for kids with rare brain cancer: targeted drug shows promise
Disease control Recruiting nowThis study tests a drug called lorlatinib in children (ages 1-21) with a newly diagnosed, aggressive brain tumor that has a specific genetic change (ALK or ROS1 fusion). The goal is to see if the drug can shrink or control the tumor and to check its safety when given alone or wit…
Matched conditions: WHO GRADE IV GLIOMA
Phase: EARLY_PHASE1 • Sponsor: Nationwide Children's Hospital • Aim: Disease control
Last updated May 20, 2026 11:55 UTC
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Brain tumor DNA test could pave way for personalized treatment in kids
Knowledge-focused Recruiting nowThis study aims to analyze the genetic makeup of brain tumors in children, teens, and young adults (ages 1 to 39) newly diagnosed with high-grade glioma, including a type called DIPG. By identifying specific genetic changes in each tumor, researchers hope to match patients with m…
Matched conditions: WHO GRADE IV GLIOMA
Sponsor: Nationwide Children's Hospital • Aim: Knowledge-focused
Last updated May 26, 2026 04:38 UTC