VULVA CANCER

This study tests a new immunotherapy for people with advanced HPV-related cancers (cervical, throat, anal, and others). Doctors take a patient's own immune cells, add a special receptor to help them find and attack HPV-infected cancer cells, and give them back. The goal is to shr…

This study tests a new drug called CNSI-Fe(II), which is injected directly into tumors. It uses iron to trigger a type of cell death called ferroptosis, aiming to shrink or control advanced solid tumors like lung, pancreas, and colorectal cancer. About 54 adults whose cancers hav…

This study is testing whether two drugs, pembrolizumab and lenvatinib, can shrink tumors in people with advanced vulvar cancer that cannot be removed by surgery. About 80 participants will receive the combination therapy. The main goals are to see how many patients respond to tre…

This study looks at new ways to detect if vulva cancer has come back after treatment. Researchers will ask 295 women to fill out surveys every four months and give blood samples to look for cancer DNA. They will compare results with a group of 1000 women treated in the past. The …

This study tests whether 3D-printed custom applicators can deliver radiation more precisely than standard cylinder applicators for gynecologic cancers like endometrial, vaginal, and vulvar cancer. Ten participants will receive brachytherapy with a personalized 3D-printed mold. Th…

This study is collecting tumor, blood, and plasma samples from over 1,000 people with certain cancers (ovarian, breast, head and neck, cervical, vulva, and sarcoma). The goal is to find new markers that link tumor genetics and immune response to how the disease behaves. Participa…