Visceral leishmaniasis
Clinical trials for Visceral leishmaniasis explained in plain language.
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New oral drug candidate for two neglected parasitic diseases enters first human testing
Cure CompletedResearchers are running a first-in-human study of LXE408, an experimental oral tablet, to see how safe and well tolerated it is in healthy adults. About 88 healthy volunteers aged 18 to 65 will receive single or multiple ascending doses of LXE408 or a placebo. The study also meas…
Matched conditions: VISCERAL LEISHMANIASIS
Phase 1 • Sponsor: Novartis Pharmaceuticals • Aim: Cure
Last updated Sep 11, 2026 00:00 UTC
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Blood tests could replace painful spleen sampling for deadly parasite
Diagnosis CompletedVisceral leishmaniasis is a fatal parasitic disease if left untreated, and current methods to check whether treatment worked require invasive sampling of the spleen or bone marrow. Researchers at Gondar University Hospital in Ethiopia are evaluating blood-based immune and molecul…
Matched conditions: VISCERAL LEISHMANIASIS
Sponsor: Foundation for Innovative New Diagnostics, Switzerland • Aim: Diagnosis
Last updated Sep 19, 2026 00:00 UTC
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Generic antifungal drug shows promise in early comparison study
Knowledge-focused CompletedThis study compared a new generic version of liposomal amphotericin B (an antifungal drug) to the brand-name version (AmBisome®) in 58 healthy Chinese adults. Each volunteer received a single dose of both drugs at different times to see if the generic works the same way in the bo…
Matched conditions: VISCERAL LEISHMANIASIS
Sponsor: Sichuan Huiyu Pharmaceutical Co., Ltd • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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Generic antifungal drug put to the test in healthy volunteers
Knowledge-focused CompletedThis study checked if a new version of the antifungal drug amphotericin B liposome works the same as the original. 42 healthy adults received a single dose of each version at different times. The goal was to see if the drug levels in the blood were similar enough to consider the …
Matched conditions: VISCERAL LEISHMANIASIS
Sponsor: Sichuan Huiyu Pharmaceutical Co., Ltd • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC