VASCULITIS

This study tests whether the drug avacopan, given alongside standard treatments, can help children aged 6 to 17 with active ANCA-associated vasculitis (a disease where the immune system attacks blood vessels) achieve remission. About 20 participants will receive avacopan plus eit…

This study tracks women with vasculitis who become pregnant to better understand how the disease affects pregnancy and what outcomes occur. Participants fill out online surveys during each trimester. No treatments or medications are tested—the goal is simply to gather information…

This study follows 100 people with relapsing polychondritis, a rare disease that causes repeated inflammation of cartilage in the ears, nose, and airways. Researchers aim to learn how the disease develops over time by collecting medical history and survey responses. No new treatm…

This study is creating a collection of blood, urine, and stool samples from 500 adults with or at risk for heart and blood vessel diseases. Researchers will use these samples to look for biological markers that could help understand these conditions better. The goal is to support…

This study follows 670 adults with vasculitis (blood vessel inflammation) to understand how the disease appears, how it is treated, and what complications arise. Participants receive standard care from their own doctors. The goal is to collect data to improve future care, not to …

This study follows 40 adults with central nervous system vasculitis (CNSV), a rare and serious inflammation of brain blood vessels that can cause strokes, memory loss, and other problems. Researchers will track participants' health history, symptoms, and treatments over time to l…

This study is creating a large collection of blood samples and medical information from 3000 people with autoimmune diseases like lupus, scleroderma, and myositis. The goal is to help researchers find new markers and develop better treatments. Participants will not receive any ex…

This study looks at whether a type of artificial intelligence (AI) can help doctors better identify complications in people with rheumatoid arthritis (RA). Researchers will use AI to suggest possible complications from patient records and see if doctors agree with and use those s…

This study looks at whether a computer program for doctors and easy-to-read brochures for patients can help adults aged 60 and older with rheumatic conditions stop or reduce medications that may be risky. Researchers will follow 100 participants for about 18 months to track medic…

This study explores whether a special type of MRI, called manganese-enhanced MRI (MEMRI), can help detect early signs of heart and kidney problems in people with various kidney diseases, including acute kidney injury, chronic kidney disease, and kidney transplant. Researchers wil…

This study looks at how the body processes high doses of the steroid prednisolone in people with inflammatory diseases like thyroid eye disease, asthma, and vasculitis. Researchers will measure drug levels in the blood and urine to compare short-term and long-term use. The goal i…

This study looks at skin samples from 50 people with different types of vasculitis, a condition where blood vessels become inflamed. Researchers want to understand how the disease affects the skin at a molecular level. Participants must have a skin rash or sore caused by active v…

This study is following 300 people with suspected or confirmed systemic vasculitis over 10 years. Researchers are collecting data on symptoms, imaging, and biomarkers to identify who is at higher risk for relapse or poor outcomes. The goal is to better understand the disease and …