Urinary bladder neoplasms
Clinical trials for Urinary bladder neoplasms explained in plain language.
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A pill instead of surgery? trial tests vepugratinib against Low-Grade bladder cancer
Disease control Not yet recruitingResearchers are testing whether an oral drug called vepugratinib can clear low-grade, intermediate-risk bladder cancer that has not invaded muscle, or low-grade upper tract urothelial cancer. The trial enrolls adults whose tumors carry a specific change in the FGFR3 gene. Partici…
Matched conditions: URINARY BLADDER NEOPLASMS
Phase 2 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Sep 20, 2026 00:00 UTC
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New hope for tough bladder cancer: immune drug plus chemo combo enters trial
Disease control Not yet recruitingThis study tests whether adding chemotherapy drugs (gemcitabine and mitomycin C) directly into the bladder alongside an immune-boosting drug (toripalimab) works better than toripalimab alone for people with a high-risk bladder cancer that did not respond to standard BCG therapy. …
Matched conditions: URINARY BLADDER NEOPLASMS
Phase 2 • Sponsor: First Affiliated Hospital of Wenzhou Medical University • Aim: Disease control
Last updated Sep 10, 2026 00:00 UTC
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Can a bladder rinse before surgery keep bladder cancer at bay?
Disease control Not yet recruitingThis phase III trial tests whether giving the drug Alpha1H directly into the bladder before standard surgery lowers the risk of cancer returning in adults with low- to intermediate-risk non-muscle-invasive bladder cancer. Participants are randomly assigned to receive either six A…
Matched conditions: URINARY BLADDER NEOPLASMS
Phase 3 • Sponsor: Hamlet Pharma AB • Aim: Disease control
Last updated Sep 06, 2026 00:00 UTC
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New hope for bladder cancer: targeted drug combo aims to boost survival
Disease control Not yet recruitingThis study tests whether a combination of disitamab vedotin (a targeted drug) and toripalimab (an immunotherapy) works better than standard chemotherapy plus immunotherapy for people with HER2-positive muscle-invasive bladder cancer. About 240 participants will receive treatment …
Matched conditions: URINARY BLADDER NEOPLASMS
Phase 2/3 • Sponsor: West China Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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Heated chemo offers new hope for bladder cancer patients facing surgery
Disease control Not yet recruitingThis study tests a treatment called HIVEC, which delivers heated chemotherapy directly into the bladder. It is for people with a type of bladder cancer that has not responded to standard therapy and who cannot have their bladder removed. The goal is to see if this approach is saf…
Matched conditions: URINARY BLADDER NEOPLASMS
Sponsor: AC.TA. S.r.l. • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Bladder cancer surgery: what happens after the bladder is removed?
Knowledge-focused Not yet recruitingThis study looks at the well-being and medical care of people in Korea who had their bladder removed (radical cystectomy) for bladder cancer. Using nationwide insurance records, researchers will track complications, hospital stays, readmissions, and survival up to three years aft…
Matched conditions: URINARY BLADDER NEOPLASMS
Sponsor: Janssen Korea, Ltd., Korea • Aim: Knowledge-focused
Last updated Aug 30, 2026 00:00 UTC
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AI doctor takes on urology: can a chatbot outperform human specialists?
Knowledge-focused Not yet recruitingThis study will test a special AI program called UroMed AI Doctor, designed to help with urology care. Researchers will compare AI-assisted care to traditional care from a specialist for patients with kidney stones, enlarged prostate, or bladder cancer. The goal is to see if the …
Matched conditions: URINARY BLADDER NEOPLASMS
Sponsor: First Affiliated Hospital of Guangxi Medical University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Scientists hunt for clues in bladder Cancer's surrounding tissue
Knowledge-focused Not yet recruitingThis study examines stored tumor samples from 100 bladder cancer patients who had their bladder removed. Researchers will measure the amount of supportive tissue, immune cells, and immune clusters near the tumor. The goal is to see if these features are linked to how long patient…
Matched conditions: URINARY BLADDER NEOPLASMS
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC