TYMPANIC MEMBRANE PERFORATION

This study tested whether a gel containing a natural growth factor (FGF-2) can safely close long-lasting holes in the eardrum. Fifty-seven adults with a dry eardrum hole for over 3 months received up to three treatments. The main goal was to see how many people's eardrums closed …

This study tested a gel containing a natural growth factor (FGF-2) to close long-lasting holes in the eardrum. 52 adults with a dry eardrum hole for at least 6 months received either the gel or a placebo up to three times. The main goal was to see if the hole closed completely, m…

This study looked at how well a special graft (the Biodesign Otologic Repair Graft) closes holes in the eardrum. 87 people who needed this repair took part. Researchers checked if the hole was completely closed 3 months after the procedure.

This study tested a gel patch called Perf-Fix that helps the body close chronic holes in the eardrum naturally. It involved 71 people aged 5 and older with large, non-healing eardrum perforations. The patch is applied in the doctor's office and cured with a light, aiming to avoid…

This study compared two surgical techniques (interlay and underlay) for repairing large eardrum holes caused by chronic ear infections. Sixty adults with hearing loss but no active infection took part. The goal was to see which method better improves hearing after surgery.

This study looked at two ways of preparing a tissue graft used to repair holes in the ear drum. 92 adults with chronic ear infections and hearing loss had surgery using either a wet or dry graft. The goal was to see which method led to better healing and hearing improvement three…

This study reviewed the medical records of 980 children who had surgery to repair a hole in their eardrum (called tympanoplasty). The goal was to see how often the eardrum closed successfully and how hearing improved after surgery. Researchers looked at results from hearing tests…