TRANSFUSION-DEPENDENT BETA-THALASSEMIA
Clinical trials for TRANSFUSION-DEPENDENT BETA-THALASSEMIA explained in plain language.
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Can metformin or hydroxyurea cut transfusions for thalassemia patients?
Disease control CompletedThis study tested two drugs, hydroxyurea and metformin, in 96 people with transfusion-dependent beta-thalassemia to see if they could reduce the need for blood transfusions. Participants took one of the drugs daily for a year. Researchers measured changes in fetal hemoglobin and …
Matched conditions: TRANSFUSION-DEPENDENT BETA-THALASSEMIA
Phase: PHASE4 • Sponsor: Bahria University • Aim: Disease control
Last updated May 26, 2026 10:02 UTC
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Could a weekly shot replace insulin for kids with thalassemia and diabetes?
Disease control CompletedThis study looked at whether a GLP-1 receptor agonist (a type of diabetes drug) is safer and more effective than standard insulin therapy for managing diabetes in children aged 10-18 with transfusion-dependent thalassemia. The trial enrolled 80 participants and measured changes i…
Matched conditions: TRANSFUSION-DEPENDENT BETA-THALASSEMIA
Phase: PHASE2 • Sponsor: Ain Shams University • Aim: Disease control
Last updated May 18, 2026 11:58 UTC
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Drug cocktail may cut transfusions for thalassemia patients
Disease control CompletedThis study tested whether a combination of two drugs, thalidomide and hydroxyurea, can reduce the need for blood transfusions in people with transfusion-dependent beta thalassemia. 100 patients aged 2 years and older took the drugs for one year. The main goal was to see if the nu…
Matched conditions: TRANSFUSION-DEPENDENT BETA-THALASSEMIA
Phase: PHASE2 • Sponsor: Pakistan Blood and Marrow Transplant (PBMT) Group • Aim: Disease control
Last updated May 12, 2026 13:40 UTC