THYROID EYE DISEASE, TED

This phase 3 trial tests whether ZL-1109 can reduce eye bulging and other symptoms in 99 Chinese adults with moderate to severe thyroid eye disease. Participants receive either the drug or a placebo, and doctors measure changes in eye position over time. The study is currently re…

This study tests a new drug called MHB018A for people with chronic moderate-to-severe thyroid eye disease, a condition that causes eye bulging and discomfort. About 150 adults aged 18-75 will receive either the drug or a placebo every 4 weeks for 6 months. The main goal is to see…

This study tests an oral medication called tofacitinib for people with moderate-to-severe thyroid eye disease who did not get better with or could not tolerate steroids. The drug works by blocking inflammation pathways. Eight participants will take tofacitinib twice daily for 24 …

This early-stage study tests a new drug called cizutamig in 38 adults with active, moderate-to-severe thyroid eye disease (TED). The main goal is to check the drug's safety and how the body processes it. Researchers will also look for signs that the drug might help control the di…

This study tests an injection called MHB018A for people with moderate-to-severe thyroid eye disease, which causes bulging eyes and discomfort. About 258 adults who completed earlier studies will receive the drug for 24 weeks to see if it reduces eye bulging and prevents symptoms …

This study tests whether statin therapy and vitamin D supplements can help control active thyroid eye disease, a condition that causes eye bulging and discomfort. About 120 adults with active disease will be randomly assigned to one of four groups: standard care alone, statin plu…

This early-stage study tests the safety of a new drug called GenSci098 in 76 adults with active thyroid eye disease (TED). Participants receive one or more injections under the skin, and researchers monitor for side effects and how the drug moves through the body. The goal is to …