THYROID EYE DISEASE

This study is testing whether an investigational drug called IBI311 can reduce eye bulging (proptosis) in people with inactive thyroid eye disease. About 111 participants will be randomly assigned to receive either IBI311 or a placebo for 24 weeks, followed by a longer follow-up …

This study is testing an investigational medicine called TOUR006 to see if it can reduce eye bulging and other symptoms in people with active Thyroid Eye Disease. About 81 participants will receive either one of two doses of TOUR006 or a placebo injection every eight weeks. The m…

This study is testing an experimental injection called AMG 732 for people with moderate-to-severe thyroid eye disease, which causes painful, bulging eyes. The research has two parts: first checking safety in healthy volunteers, then testing if the treatment reduces eye bulging an…

This early-stage study is testing the safety of an oral medication called K9 for people with active Thyroid Eye Disease (TED). Up to 10 patients will take the pill twice daily for up to 24 weeks, with doctors closely monitoring for side effects. The study will also track changes …

This study is testing a medication called Teprotumumab N01 for people with active Thyroid Eye Disease (TED), a condition that causes eye bulging, double vision, and swelling. Fifty participants will receive the drug and have their eye symptoms and quality of life tracked for 24 w…

This study aims to understand how the body processes and breaks down a common anti-inflammatory steroid medication called prednisolone when given at high doses. Researchers will measure drug levels in the blood and urine of 120 patients who are taking high doses of prednisolone f…