THORACOABDOMINAL AORTIC ANEURYSM

This study tests a stent graft that doctors modify by hand to treat complex aortic aneurysms in patients who cannot use standard FDA-approved devices. About 40 high-risk adults will receive the custom graft and be followed for five years to check safety and effectiveness. The goa…

This study is tracking 760 people who receive custom-made stents to repair complex aneurysms in the main artery of the chest and belly. The goal is to see how safe and effective these stents are, and how they affect quality of life. Participants must have a large or fast-growing …

This study is testing a new device called a stent graft to treat thoracoabdominal aortic aneurysms, a life-threatening bulge in the main artery. The device is placed inside the artery through a small cut, avoiding major surgery. The study will include 11 adults aged 18 to 80 and …

This study compares two ways to keep blood flowing during open surgery for a large aneurysm in the chest and belly. About 236 adults will be randomly assigned to one of two heart-lung machine techniques. Researchers will track serious complications like death, stroke, kidney fail…

This study compares two ways to treat complex abdominal aortic aneurysms (a bulging blood vessel in the belly). One method uses a custom-made stent-graft, the other uses a stent-graft shaped with the help of a 3D-printed model of the patient's aorta. The goal is to see which appr…

This study is tracking how well a special stent device works for people with a bulging blood vessel (aneurysm) in the chest and belly area. About 100 patients will be followed for a year to see if the device stays in place, keeps blood flowing, and avoids serious problems like ru…

This study tests a new technique called BAO-G that uses special stents to repair complex aortic aneurysms (bulging blood vessels) in the chest and belly. The goal is to see if it is safe and works well over 5 years. About 60 adults with large aneurysms will take part. The approac…

This study tests whether grafts modified by doctors during surgery can safely repair complex aortic aneurysms in patients who are too high-risk for standard surgery. About 220 participants with different types of aortic damage will be followed for up to 5 years to check survival,…

This study looks at how safe and effective custom-made stent grafts are for treating complex aneurysms in the main artery near the kidneys and chest. About 50 people who are too high-risk for open surgery will receive these grafts. The goal is to see if the grafts work well and t…

This study tests a minimally invasive procedure to treat large aneurysms in the aorta (the main artery) in the chest and belly area. Instead of open surgery, doctors place a fabric-covered metal tube (stent-graft) inside the aneurysm to seal it off. The goal is to see if this app…

This study tests three custom-made stents for people with complex aortic aneurysms that standard devices can't treat. The goal is to see if these stents reduce deaths, lung problems, and hospital stays. About 410 adults with certain types of aortic aneurysms will take part.

This study is testing whether a low dose of ketamine can reduce the amount of strong painkillers (opioids) needed and improve pain control in people recovering from thoracic endovascular aortic repair (TEVAR). About 30 adults scheduled for this surgery will receive either ketamin…

This study is collecting information from 600 patients across Europe who receive Cook's custom-made stent-grafts to treat complex aortic aneurysms and chronic aortic dissections. The goal is to see how well the devices work in everyday medical practice and to monitor safety. The …