Systemic scleroderma
Clinical trials for Systemic scleroderma explained in plain language.
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Can a One-Time cell therapy reset the immune system in autoimmune disease?
Cure Not yet recruitingThis trial is testing an experimental treatment called CRT-402 for people with severe autoimmune diseases like lupus, scleroderma, and myositis that haven't improved with standard therapies. CRT-402 is a type of CAR-T cell therapy given by infusion that aims to deplete certain im…
Matched conditions: SYSTEMIC SCLERODERMA
Phase 1/2 • Sponsor: Myeloid Therapeutics • Aim: Cure
Last updated Aug 23, 2026 00:00 UTC
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New antibody drug firsekibart tested for scleroderma skin thickening
Disease control Not yet recruitingThis early-stage trial will test a new drug called firsekibart in 30 people with systemic sclerosis (scleroderma), a disease that causes skin thickening and organ damage. Firsekibart is an antibody that blocks a protein involved in inflammation. The study will measure changes in …
Matched conditions: SYSTEMIC SCLERODERMA
Sponsor: Tongji Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:09 UTC
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Fat stem cells injected into face could ease scleroderma mouth stiffness
Symptom relief Not yet recruitingThis study tests whether injections of stem cells from donated fat tissue can help loosen mouth fibrosis in people with systemic scleroderma. Fifty adults with limited mouth opening will receive either stem cell or placebo injections around the mouth and be followed for 24 weeks.…
Matched conditions: SYSTEMIC SCLERODERMA
Phase 2 • Sponsor: University Hospital, Toulouse • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC