SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

This study tested two experimental drugs, VAY736 and CFZ533, in 107 people with systemic lupus erythematosus (SLE). The goal was to see if these treatments could reduce lupus disease activity and allow patients to lower their steroid doses. Participants received either one of the…

This study tested an experimental drug called EG-501 for people with lupus who experience cognitive impairment, often called "brain fog." The trial involved 131 participants who received either the drug or a placebo for 14 weeks. The goal was to see if EG-501 could safely improve…

This study tested an 8-session online health coaching program for women with lupus. The program helped participants set personal goals to manage fatigue, pain, and brain fog — symptoms that often aren't addressed in regular doctor visits. 36 people took part to see if the program…

This study looked at how the immune system works in people with lupus (SLE) and mixed connective tissue disease (MCTD). Researchers studied 124 participants to understand immune cell behavior, genetic factors, and how these diseases progress over time. The goal was to gather know…

This study looked at 271 children and adults with lupus to find genetic and immune system differences. The goal was to identify gene mutations linked to the disease, especially in children. Researchers hope this will lead to a better understanding of what causes lupus and how it …

This study tested a program where a patient navigator helped minority adults with lupus overcome barriers to care, like scheduling appointments, arranging transportation, and understanding their health. The goal was to see if this support could improve quality of life and medicat…

This study created a registry to collect medical information from 868 patients with Anti-Phospholipid Syndrome (APS) and/or Systemic Lupus Erythematosus (SLE). The goal was to better understand these autoimmune conditions. No treatments were tested; the focus was on gathering dat…