STIFF-PERSON SYNDROME
Clinical trials for STIFF-PERSON SYNDROME explained in plain language.
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Experimental CAR T-Cell therapy targets rare stiff person syndrome
Disease control OngoingThis phase 2 trial is testing a new treatment called KYV-101 for people with stiff person syndrome (SPS) that hasn't improved with standard therapies. The treatment uses a patient's own immune cells, modified to target and attack certain immune cells that may be causing the disea…
Matched conditions: STIFF-PERSON SYNDROME
Phase: PHASE2 • Sponsor: Kyverna Therapeutics • Aim: Disease control
Last updated Jun 23, 2026 20:33 UTC
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Engineered immune cells take on lupus and scleroderma in early trial
Disease control ENROLLING_BY_INVITATIONThis early-phase study tests a new treatment called Prula-cel for people with autoimmune diseases like lupus, scleroderma, and vasculitis. Prula-cel uses donor immune cells engineered to target and destroy faulty immune cells that attack the body. The goal is to find a safe dose …
Matched conditions: STIFF-PERSON SYNDROME
Phase: PHASE1 • Sponsor: Adicet Therapeutics • Aim: Disease control
Last updated Jun 09, 2026 12:09 UTC
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Powerful chemo and stem cell transplant may tame severe autoimmune nerve diseases
Disease control OngoingThis study tests a strong chemotherapy combination followed by a stem cell transplant in 53 people with autoimmune neurologic diseases (like multiple sclerosis or stiff person syndrome) that did not improve with standard treatments. The goal is to weaken the overactive immune sys…
Matched conditions: STIFF-PERSON SYNDROME
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Jun 08, 2026 13:08 UTC