STAGE III PROSTATE CANCER AJCC V8
Clinical trials for STAGE III PROSTATE CANCER AJCC V8 explained in plain language.
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Prostate cancer trial aims to tailor treatment based on genetic risk
Disease control OngoingThis study tests whether men with high-risk prostate cancer can receive treatment tailored to their genetic risk score. Those with a low genetic risk may get a shorter course of hormone therapy (12 months instead of 24) plus radiation, while those with a high genetic risk get an …
Matched conditions: STAGE III PROSTATE CANCER AJCC V8
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated May 22, 2026 14:04 UTC
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New drug cocktail aims to supercharge immune attack on prostate cancer before surgery
Disease control OngoingThis study tests whether giving a combination of drugs (enteric-coated aspirin, rintatolimod, and possibly interferon-alpha 2b) before prostate cancer surgery can help the immune system fight the tumor more effectively. About 12 men with early-stage prostate cancer who are schedu…
Matched conditions: STAGE III PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: Roswell Park Cancer Institute • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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Immunotherapy plus chemo shows promise against Tough-to-Treat cancers
Disease control OngoingThis early-phase trial studies whether adding the immunotherapy drug pembrolizumab to standard chemotherapy can help people with rare, aggressive small cell or neuroendocrine cancers of the bladder or prostate. About 15 participants with cancer that has spread will receive the co…
Matched conditions: STAGE III PROSTATE CANCER AJCC V8
Phase: PHASE1 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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Bladder lift may cut incontinence after prostate surgery
Symptom relief TerminatedThis study tests whether adding a procedure called vesicopexy (lifting the bladder back to its normal position) to standard robotic prostate cancer surgery helps men regain bladder control faster. About 196 men with early-stage prostate cancer will be randomly assigned to receive…
Matched conditions: STAGE III PROSTATE CANCER AJCC V8
Phase: NA • Sponsor: University of Southern California • Aim: Symptom relief
Last updated May 26, 2026 08:13 UTC
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Lifestyle coaching aims to boost quality of life for prostate cancer patients
Symptom relief OngoingThis study tests a lifestyle program called Watchful Living for Black and Hispanic men with early-stage prostate cancer who are on active surveillance, along with their partners. The program includes coaching calls and nutrition sessions to improve quality of life, physical activ…
Matched conditions: STAGE III PROSTATE CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated May 22, 2026 14:03 UTC
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Prostate cancer treatment may harm your heart – new study investigates
Knowledge-focused OngoingThis study looks at how hormone therapy for prostate cancer affects the heart. Researchers will compare three treatment groups: radiation alone, radiation with leuprolide, and radiation with relugolix. The goal is to understand why some men develop heart problems and find ways to…
Matched conditions: STAGE III PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: Emory University • Aim: Knowledge-focused
Last updated May 20, 2026 11:56 UTC